• Minireview  28 February 2019

    Unraveling the Paradoxical Action of Androgens on Muscle Stem Cells

    Androgens act in almost all tissues throughout the lifetime and have important roles in skeletal muscles. The levels of androgens increase during puberty and remain sustained at high levels in adulthood. Because androgens have an anabolic effect on skeletal muscles and muscle stem cells, these increased levels of androgens after puberty should lead to spontaneous muscle hypertrophy and hyperplasia in adulthood. However, the maintenance of muscle volume, myonuclei number per myofiber, and quie ...

  • Article  28 February 2019

    HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells

    Lysophosphatidic acid (LPA) is an endogenous lysophospholipid with signaling properties outside of the cell and it signals through specific G protein-coupled receptors, known as LPA1?6. For one of its receptors, LPA1 (gene name Lpar1), details on the cis-acting elements for transcriptional control have not been defined. Using 5′RACE analysis, we report the identification of an alternative transcription start site of mouse Lpar1 and cha ...

  • Minireview  28 February 2019

    Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging

    Tracking the fate of individual cells and their progeny through lineage tracing has been widely used to investigate various biological processes including embryonic development, homeostatic tissue turnover, and stem cell function in regeneration and disease. Conventional lineage tracing involves the marking of cells either with dyes or nucleoside analogues or genetic marking with fluorescent and/or colorimetric protein reporters. Both are imaging-based approaches that have played a crucial ro ...

  • Article  28 February 2019

    Loss of Primary Cilia Results in the Development of Cancer in the Murine Thyroid Gland

    Communications at the interface between the apical membrane of follicular cells and the follicular lumen are critical for the homeostasis of thyroid gland. Primary cilia at the apical membrane of thyroid follicular cells may sense follicular luminal environment and regulate follicular homeostasis, although their role in vivo remains to be determined. Here, mice devoid of primary cilia were generated by thyroid follicular epithelial cell-specific deletion of the gene encoding ...


Mol. Cells 2019; 42(2): 97~188
Minireviews
Unraveling the Paradoxical Action of Androgens on Muscle Stem Cells
Ji-Yun Seo, Ji-Hoon Kim, and Young-Yun Kong
Mol. Cells 2019; 42(2): 97-103  https://doi.org/10.14348/molcells.2019.0004 PDF PubReader Google Scholar Search
Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging
Szu-Hsien (Sam) Wu, Ji-Hyun Lee, and Bon-Kyoung Koo
Mol. Cells 2019; 42(2): 104-112  https://doi.org/10.14348/molcells.2019.0006 PDF PubReader Google Scholar Search
Articles
Loss of Primary Cilia Results in the Development of Cancer in the Murine Thyroid Gland
Junguee Lee, Shinae Yi, Joon Young Chang, Jung Tae Kim, Hae Joung Sul, Ki Cheol Park, Xuguang Zhu, Sheue-yann Cheng, Jukka Kero, Joon Kim, and Minho Shong
Mol. Cells 2019; 42(2): 113-122  https://doi.org/10.14348/molcells.2018.0430 PDF PubReader Supplementary File(s) Google Scholar Search
HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells
Nam-Ho Kim, Ali Sadra, Hee-Young Park, Sung-Min Oh, Jerold Chun, Jeong Kyo Yoon, and Sung-Oh Huh
Mol. Cells 2019; 42(2): 123-134  https://doi.org/10.14348/molcells.2018.0399 PDF PubReader Google Scholar Search
OCT4B Isoform Promotes Anchorage-Independent Growth of Glioblastoma Cells
Sang-Hun Choi, Jun-Kyum Kim, Hee-Young Jeon, Kiyoung Eun, and Hyunggee Kim
Mol. Cells 2019; 42(2): 135-142  https://doi.org/10.14348/molcells.2018.0311 PDF PubReader Supplementary File(s) Google Scholar Search
Role of Dehydrocorybulbine in Neuropathic Pain After Spinal Cord Injury Mediated by P2X4 Receptor
Zhongwei Wang, Wei Mei, Qingde Wang, Rundong Guo, Peilin Liu, Yuqiang Wang, Zijuan Zhang, and Limin Wang
Mol. Cells 2019; 42(2): 143-150  https://doi.org/10.14348/molcells.2018.0028 PDF PubReader Supplementary File(s) Google Scholar Search
Alleviation of Ultraviolet-B Radiation-Induced Photoaging by a TNFR Antagonistic Peptide, TNFR2-SKE
Kyoung-Jin Lee, Kyeong Han Park, and Jang-Hee Hahn
Mol. Cells 2019; 42(2): 151-160  https://doi.org/10.14348/molcells.2018.0423 PDF PubReader Supplementary File(s) Google Scholar Search
TGFBI Promoter Methylation is Associated with Poor Prognosis in Lung Adenocarcinoma Patients
Yangki Seok, Won Kee Lee, Jae Yong Park, and Dong Sun Kim
Mol. Cells 2019; 42(2): 161-165  https://doi.org/10.14348/molcells.2018.0322 PDF PubReader Supplementary File(s) Google Scholar Search
A Genome-Scale Co-Functional Network of Xanthomonas Genes Can Accurately Reconstruct Regulatory Circuits Controlled by Two-Component Signaling Systems
Hanhae Kim, Anna Joe, Muyoung Lee, Sunmo Yang, Xiaozhi Ma, Pamela C. Ronald, and Insuk Lee
Mol. Cells 2019; 42(2): 166-174  https://doi.org/10.14348/molcells.2018.0403 PDF PubReader Supplementary File(s) Google Scholar Search
The MicroRNA-551a/MEF2C Axis Regulates the Survival and Sphere Formation of Cancer Cells in Response to 5-Fluorouracil
Hoin Kang, Chongtae Kim, Eunbyul Ji, Sojin Ahn, Myeongwoo Jung, Youlim Hong, WooK Kim, and Eun Kyung Lee
Mol. Cells 2019; 42(2): 175-182  https://doi.org/10.14348/molcells.2018.0288 PDF PubReader Google Scholar Search
Rapid Report
Calcium-Phosphate Crystals Promote RANKL Expression via the Downregulation of DUSP1
YunJeong Choi, Ji Hyun Yoo, Youngkyun Lee, Moon Kyoung Bae, and Hyung Joon Kim
Mol. Cells 2019; 42(2): 183-188  https://doi.org/10.14348/molcells.2018.0382 PDF PubReader Google Scholar Search
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Current Issue

28 February 2019
Volume 42,
Number 2,
pp. 97~188
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*


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