• Minireview  31 August 2017

    Application of Functional Near-Infrared Spectroscopy to the Study of Brain Function in Humans and Animal Models

    Functional near-infrared spectroscopy (fNIRS) is a noninvasive optical imaging technique that indirectly assesses neuronal activity by measuring changes in oxygenated and deoxygenated hemoglobin in tissues using near-infrared light. fNIRS has been used not only to investigate cortical activity in healthy human subjects and animals but also to reveal abnormalities in brain function in patients suffering from neurological and psychiatric disorders and in animals that exhibit disease conditions. ...

  • Minireview  31 August 2017

    Engineering and Application of Zinc Finger Proteins and TALEs for Biomedical Research

    Engineered DNA-binding domains provide a powerful technology for numerous biomedical studies due to their ability to recognize specific DNA sequences. Zinc fingers (ZF) are one of the most common DNA-binding domains and have been extensively studied for a variety of applications, such as gene regulation, genome engineering and diagnostics. Another novel DNA-binding domain known as a transcriptional activator-like effector (TALE) has been more recently discovered, which has a previously undesc ...

  • Article  31 August 2017

    Effects of Adenoviral Gene Transduction on the Stemness of Human Bone Marrow Mesenchymal Stem Cells

    Human mesenchymal stem cells (MSCs) are currently being evaluated as a cell-based therapy for tissue injury and degenerative diseases. Recently, several methods have been suggested to further enhance the therapeutic functions of MSCs, including genetic modifications with tissue- and/or disease-specific genes.

    The objective of this study was to examine the efficiency and stability of transduction using an adenoviral vector in human MSCs. Additionally, we aimed to assess the effects of tr ...

  • Article  31 August 2017

    Adverse Effect of Superovulation Treatment on Maturation, Function and Ultrastructural Integrity of Murine Oocytes

    Regular monitoring on experimental animal management found the fluctuation of ART outcome, which showed a necessity to explore whether superovulation treatment is responsible for such unexpected outcome. This study was subsequently conducted to examine whether superovulation treatment can preserve ultrastructural integrity and developmental competence of oocytes following oocyte activation and embryo culture. A randomized study using mouse model was designed and in vitro development (experime ...

Mol. Cells 2017; 40(9): 607~695
Autophagy Is Pro-Senescence When Seen in Close-Up, but Anti-Senescence in Long-Shot
Yoojin Kwon, Ji Wook Kim, Jo Ae Jeoung, Mi-Sung Kim, and Chanhee Kang
Mol. Cells 2017; 40(9): 607-612  https://doi.org/10.14348/molcells.2017.0151 PDF PubMed PubReader Google Scholar Search
Molecular and Cellular Basis of Neurodegeneration in Alzheimer’s Disease
Sangyun Jeong
Mol. Cells 2017; 40(9): 613-620  https://doi.org/10.14348/molcells.2017.0096 PDF PubMed PubReader Google Scholar Search
Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer
Namgyu Lee, Dae-Kyum Kim, Seung Hyun Han, Hye Guk Ryu, Sung Jin Park, Kyong-Tai Kim, and Kwan Yong Choi
Mol. Cells 2017; 40(9): 621-631  https://doi.org/10.14348/molcells.2017.0108 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Inhibition of the DevSR Two-Component System by Overexpression of Mycobacterium tuberculosis PknB in Mycobacterium smegmatis
Hyun-Jung Bae, Ha-Na Lee, Mi-Na Baek, Eun-Jin Park, Chi-Yong Eom, In-Jeong Ko, Ho-Young Kang, and Jeong-Il Oh
Mol. Cells 2017; 40(9): 632-642  https://doi.org/10.14348/molcells.2017.0076 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
The Roles of the SNARE Protein Sed5 in Autophagy in Saccharomyces cerevisiae
Shenshen Zou, Dan Sun, and Yongheng Liang
Mol. Cells 2017; 40(9): 643-654  https://doi.org/10.14348/molcells.2017.0030 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Generation, Diversity Determination, and Application to Antibody Selection of a Human Naïve Fab Library
Sangkyu Kim, Insoo Park, Seung Gu Park, Seulki Cho, Jin Hong Kim, Nagesh S. Ipper, Sun Shim Choi, Eung Suk Lee, and Hyo Jeong Hong
Mol. Cells 2017; 40(9): 655-666  https://doi.org/10.14348/molcells.2017.0106 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription
Sang Kyung Byun, Tae Hyeon An, Min Jeong Son, Da Som Lee, Hyun Sup Kang, Eun-Woo Lee, Baek Soo Han, Won Kon Kim, Kwang-Hee Bae, Kyoung-Jin Oh, and Sang Chul Lee
Mol. Cells 2017; 40(9): 667-676  https://doi.org/10.14348/molcells.2017.0116 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Vitamin D Proliferates Vaginal Epithelium through RhoA Expression in Postmenopausal Atrophic Vagina tissue
Arum Lee, Man Ryul Lee, Hae-Hyeog Lee, Yeon-Suk Kim, Jun-Mo Kim, Temuulee Enkhbold, and Tae-Hee Kim
Mol. Cells 2017; 40(9): 677-684  https://doi.org/10.14348/molcells.2017.0026 PDF PubMed PubReader Google Scholar Search
A Proteomics Based Approach Reveals Differential Regulation of Visceral Adipose Tissue Proteins between Metabolically Healthy and Unhealthy Obese Patients
Assim A. Alfadda, Afshan Masood, Mohammed Y. Al-Naami, Pierre Chaurand, and Hicham Benabdelkamel
Mol. Cells 2017; 40(9): 685-695  https://doi.org/10.14348/molcells.2017.0073 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
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Current Issue

30 September 2017
Volume 40,
Number 9,
pp. 607~695
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

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