• Minireview  31 May 2017

    The Expanding Significance of Inositol Polyphosphate Multikinase as a Signaling Hub

    The inositol polyphosphates are a group of multifunctional signaling metabolites whose synthesis is catalyzed by a family of inositol kinases that are evolutionarily conserved from yeast to humans. Inositol polyphosphate multikinase (IPMK) was first identified as a subunit of the arginine-responsive transcription complex in budding yeast. In addition to its role in the production of inositol tetrakis- and pentakisphosphates (IP4 and IP5), IPMK also exhibits phosphatidyli ...

  • Article  31 May 2017

    Characterization of αX I-Domain Binding to Receptors for Advanced Glycation End Products (RAGE)

    The β2 integrins are cell surface transmembrane proteins regulating leukocyte functions, such as adhesion and migration. Two members of β2 integrin, αMβ2 and αXβ2, share the leukocyte distribution profile and integrin αXβ2 is involved in antigen presentation in dendritic cells and transendothelial migration of monocytes and macrophages to atherosclerotic lesions. Receptor for advanced glycation e

  • Article  31 May 2017

    Methylation Levels of LINE-1 As a Useful Marker for Venous Invasion in Both FFPE and Frozen Tumor Tissues of Gastric Cancer

    Long interspersed nuclear element-1 (LINE-1) is a retrotransposon that contains a CpG island in its 5′-untranslated region. The CpG island of LINE-1 is often heavily methylated in normal somatic cells, which is associated with poor prognosis in various cancers. DNA methylation can differ between formalin-fixed paraffin-embedded (FFPE) and frozen tissues. Therefore, this study aimed to compare the LINE-1 methylation status between the two tissue-storage conditions in gastric cancer (GC) clin ...

  • Article  31 May 2017

    Involvement of a Gr2a-Expressing Drosophila Pharyngeal Gustatory Receptor Neuron in Regulation of Aversion to High-Salt Foods

    Regulation of feeding is essential for animal survival. The pharyngeal sense organs can act as a second checkpoint of food quality, due to their position between external taste organs such as the labellum which initially assess food quality, and the digestive tract. Growing evidence provides support that the pharyngeal sensory neurons regulate feeding, but much is still unknown. We found that a pair of gustatory receptor neurons in the LSO, a Drosophila adult pharyngeal organ ...

Mol. Cells 2017; 40(7): 441~522
Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy
Chang Hoon Ji, and Yong Tae Kwon
Mol. Cells 2017; 40(7): 441-449  https://doi.org/10.14348/molcells.2017.0115 PDF PubMed PubReader Google Scholar Search
Implications of Circadian Rhythm in Dopamine and Mood Regulation
Jeongah Kim, Sangwon Jang, Han Kyoung Choe, Sooyoung Chung, Gi Hoon Son, and Kyungjin Kim
Mol. Cells 2017; 40(7): 450-456  https://doi.org/10.14348/molcells.2017.0065 PDF PubReader Google Scholar Search
CHOP Deficiency Ameliorates ERK5 Inhibition-Mediated Exacerbation of Streptozotocin-Induced Hyperglycemia and Pancreatic β-Cell Apoptosis
Dae-Hwan Nam, Jung-Hwa Han, Jae Hyang Lim, Kwon Moo Park, and Chang-Hoon Woo
Mol. Cells 2017; 40(7): 457-465  https://doi.org/10.14348/molcells.2017.2296 PDF PubMed PubReader Google Scholar Search
Assessment of the Therapeutic Potential of Persimmon Leaf Extract on Prediabetic Subjects
Mohd M. Khan, Bao Quoc Tran, Yoon-Jin Jang, Soo-Hyun Park, William E. Fondrie, Khadiza Chowdhury, Sung Hwan Yoon, David R. Goodlett, Soo-Wan Chae, Han-Jung Chae, Seung-Young Seo, and Young Ah Goo
Mol. Cells 2017; 40(7): 466-475  https://doi.org/10.14348/molcells.2017.2298 PDF PubMed PubReader Google Scholar Search
O-GlcNAcylation of NF-κB Promotes Lung Metastasis of Cervical Cancer Cells via Upregulation of CXCR4 Expression
Akhtar Ali, Sung Hwan Kim, Min Jun Kim, Mee Young Choi, Sang Soo Kang, Gyeong Jae Cho, Yoon Sook Kim, Jun-Young Choi, and Wan Sung Choi
Mol. Cells 2017; 40(7): 476-484  https://doi.org/10.14348/molcells.2017.2309 PDF PubMed PubReader Google Scholar Search
Oleanolic Acid Promotes Neuronal Differentiation and Histone Deacetylase 5 Phosphorylation in Rat Hippocampal Neurons
Hye-Ryeong Jo, Sung Eun Wang, Yong-Seok Kim, Chang Ho Lee, and Hyeon Son
Mol. Cells 2017; 40(7): 485-494  https://doi.org/10.14348/molcells.2017.0034 PDF PubMed PubReader Google Scholar Search
5-Hydroxytryptamine 6 Receptor (5-HT6R)-Mediated Morphological Changes via RhoA-Dependent Pathways
Md. Ataur Rahman, Hanna Kim, Kang Ho Lee, Hyung-Mun Yun, Jung-Hwa Hong, Youngjae Kim, Hyunah Choo, Mikyoung Park, and Hyewhon Rhim
Mol. Cells 2017; 40(7): 495-502  https://doi.org/10.14348/molcells.2017.0080 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and Mitophagy
Seon Beom Song, So-Young Jang, Hyun Tae Kang, Bie Wei, Un-woo Jeoun, Gye Soon Yoon, and Eun Seong Hwang
Mol. Cells 2017; 40(7): 503-514  https://doi.org/10.14348/molcells.2017.0081 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
CD133 Regulates IL-1β Signaling and Neutrophil Recruitment in Glioblastoma
Seon Yong Lee, Jun-Kyum Kim, Hee-Young Jeon, Seok Won Ham, and Hyunggee Kim
Mol. Cells 2017; 40(7): 515-522  https://doi.org/10.14348/molcells.2017.0089 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
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Current Issue

31 July 2017
Volume 40,
Number 7,
pp. 441~522
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

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