• Research Article  31 May 2019

    Overexpression of RICE FLOWERING LOCUS T 1 (RFT1) Induces Extremely Early Flowering in Rice

    RICE FLOWERING LOCUS T 1 (RFT1) is a major florigen that functions to induce reproductive development in the shoot apical meristem (SAM). To further our study of RFT1, we overexpressed the gene and examined the expression patterns of major regulatory genes during floral transition and inflorescence development. Overexpression induced extremely early flowering in the transgenics, and a majority of those calli directly formed spikelets with a few spikelets, thus bypassing norma ...

  • Research Article  31 May 2019

    Silence of LncRNA GAS5 Protects Cardiomyocytes H9c2 against Hypoxic Injury via Sponging miR-142-5p

    The regulatory role of long noncoding RNA (lncRNA) growth arrest-specific transcript 5 (GAS5) in both cancerous and noncancerous cells have been widely reported. This study aimed to evaluate the role of lncRNA GAS5 in heart failure caused by myocardial infarction. We reported that silence of lncRNA GAS5 attenuated hypoxia-triggered cell death, as cell viability was increased and apoptosis rate was decreased. This phenomenon was coupled with t ...

  • Minireview  31 May 2019

    Site-Specific Labeling of Proteins Using Unnatural Amino Acids

    Labeling of a protein with a specific dye or tag at defined positions is a critical step in tracing the subtle behavior of the protein and assessing its cellular function. Over the last decade, many strategies have been developed to achieve selective labeling of proteins in living cells. In particular, the site-specific unnatural amino acid (UAA) incorporation technique has gained increasing attention since it enables attachment of various organic probes to a specific position of a protein in ...

  • Minireview  31 May 2019

    Non-Coding RNAs in Caenorhabditis elegans Aging

    Non-coding RNAs (ncRNAs) comprise various RNA species, including small ncRNAs and long ncRNAs (lncRNAs). ncRNAs regulate various cellular processes, including transcription and translation of target messenger RNAs. Recent studies also indicate that ncRNAs affect organismal aging and conversely aging influences ncRNA levels. In this review, we discuss our current understanding of the roles of ncRNAs in aging and longevity, focusing on recent advances using the roundworm Caenorhabditis ...


Mol. Cells 2019; 42(6): 441~501
Minireview
Neurodevelopmental Aspects of RASopathies
Ye Eun Kim and Seung Tae Baek
Mol. Cells 2019; 42(6): 441-447  https://doi.org/10.14348/molcells.2019.0037 PDF Google Scholar Search
Research Articles
Combination Therapy with a PI3K/mTOR Dual Inhibitor and Chloroquine Enhances Synergistic Apoptotic Cell Death in Epstein–Barr Virus-Infected Gastric Cancer Cells
Mi-Young Kim, Annie J. Kruger, Ju-Yeon Jeong, Jaehee Kim, Phil kyung Shin, Sun Young Kim, Joo Young Cho, Ki Baik Hahm, and Sung Pyo Hong
Mol. Cells 2019; 42(6): 448-459  https://doi.org/10.14348/molcells.2019.2395 PDF Supplementary File(s) Google Scholar Search
Crystal Structure of a Highly Thermostable α-Carbonic Anhydrase from Persephonella marina EX-H1
Subin Kim, Jongmin Sung, Jungyoon Yeon, Seung Hun Choi, and Mi Sun Jin
Mol. Cells 2019; 42(6): 460-469  https://doi.org/10.14348/molcells.2019.0029 PDF Supplementary File(s) Google Scholar Search
The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine
Jeong Nam Kim and Byung Joo Kim
Mol. Cells 2019; 42(6): 470-479  https://doi.org/10.14348/molcells.2019.0028 PDF Google Scholar Search
Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates
Sangwoo Ham, Hyojung Kim, Seojin Hwang, Hyunook Kang, Seung Pil Yun, Sangjune Kim, Donghoon Kim, Hyun Sook Kwon, Yun-Song Lee, MyoungLae Cho, Heung-Mook Shin, Heejung Choi, Ka Young Chung, Han Seok Ko, Gum Hwa Lee, and Yunjong Lee
Mol. Cells 2019; 42(6): 480-494  https://doi.org/10.14348/molcells.2019.0091 PDF Supplementary File(s) Google Scholar Search
Heterogeneous Sequences of Brain Cytoplasmic 200 RNA Formed by Multiple Adenine Nucleotide Insertions
Heegwon Shin, Jungmin Lee, Youngmi Kim, Seonghui Jang, Meehyein Kim, and Younghoon Lee
Mol. Cells 2019; 42(6): 495-500  https://doi.org/10.14348/molcells.2019.0108 PDF Google Scholar Search
Erratum
Erratum to: Roles of Endoplasmic Reticulum Stress in Immune Responses
Jae-Seon So
Mol. Cells 2019; 42(6): 501-501  https://doi.org/10.14348/molcells.2019.1241 PDF Google Scholar Search
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Current Issue

30 June 2019
Volume 42,
Number 6,
pp. 441~501
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*


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