• Research Article  31 August 2020

    Evolutionary and Functional Analysis of Korean Native Pig Using Single Nucleotide Polymorphisms

    Time and cost-effective production of next-generation sequencing data has enabled the performance of population-scale comparative and evolutionary studies for various species, which are essential for obtaining the comprehensive insight into molecular mechanisms underlying species- or breed-specific traits. In this study, the evolutionary and functional analysis of Korean native pig (KNP) was performed using single nucleotide polymorphism (SNP) data by comparative and population genomic approache ...

  • Research Article  31 August 2020

    WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation

    The migration, dedifferentiation, and proliferation of vascular smooth muscle cells (VSMCs) are responsible for intimal hyperplasia, but the mechanism of this process has not been elucidated. WD repeat domain 1 (WDR1) promotes actin-depolymerizing factor (ADF)/cofilin-mediated depolymerization of actin filaments (F-actin). The role of WDR1 in neointima formation and progression is still unknown. A model of intimal thickening was constructed by ligating the left common carotid artery in Wdr1

  • Research Article  31 August 2020

    Cleavage-Dependent Activation of ATP-Dependent Protease HslUV from Staphylococcus aureus

    HslUV is a bacterial heat shock protein complex consisting of the AAA+ ATPase component HslU and the protease component HslV. HslV is a threonine (Thr) protease employing the N-terminal Thr residue in the mature protein as the catalytic residue. To date, HslUV from Gram-negative bacteria has been extensively studied. However, the mechanisms of action and activation of HslUV from Gram-positive bacteria, which have an additional N-terminal sequence before the catalytic Thr residue, remain to be re ...

  • Minireview  31 August 2020

    Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders

    Autophagy is an intracellular degradation system that breaks down damaged organelles or damaged proteins using intracellular lysosomes. Recent studies have also revealed that various forms of selective autophagy play specific physiological roles under different cellular conditions. Lipid droplets, which are mainly found in adipocytes and hepatocytes, are dynamic organelles that store triglycerides and are critical to health. Lipophagy is a type of selective autophagy that targets lipid droplets ...

Mol. Cells 2020; 43(9): 763~840
Classifying the Linkage between Adipose Tissue Inflammation and Tumor Growth through Cancer-Associated Adipocytes
Yae Chan Song , Seung Eon Lee , Young Jin , Hyun Woo Park , Kyung-Hee Chun , and Han-Woong Lee
Mol. Cells 2020; 43(9): 763-773  https://doi.org/10.14348/molcells.2020.0118 PDF PubMed Google Scholar Search
WNT Signaling in Lung Repair and Regeneration
Ahmed A. Raslan and Jeong Kyo Yoon
Mol. Cells 2020; 43(9): 774-783  https://doi.org/10.14348/molcells.2020.0059 PDF PubMed Google Scholar Search
Research Articles
Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase
Zhili Rao , So Young Kim , Xiaotong Li , Da Som Kim , Yong Ju Kim , and Jung Hee Park
Mol. Cells 2020; 43(9): 784-792  https://doi.org/10.14348/molcells.2020.0136 PDF PubMed Supplementary File(s) Google Scholar Search
MicroRNA 449c Mediates the Generation of Monocytic Myeloid-Derived Suppressor Cells by Targeting STAT6
Xiaoqing Han , Tao Luan , Yingying Sun , Wenyi Yan , Dake Wang , and Xianlu Zeng
Mol. Cells 2020; 43(9): 793-803  https://doi.org/10.14348/molcells.2020.2307 PDF PubMed Supplementary File(s) Google Scholar Search
EMPAS: Electron Microscopy Screening for Endogenous Protein Architectures
Gijeong Kim , Seongmin Jang , Eunhye Lee , and Ji-Joon Song
Mol. Cells 2020; 43(9): 804-812  https://doi.org/10.14348/molcells.2020.0163 PDF Supplementary File(s) Google Scholar Search
Peroxiredoxin 3 Has Important Roles on Arsenic Trioxide Induced Apoptosis in Human Acute Promyelocytic Leukemia Cell Line via Hyperoxidation of Mitochondrial Specific Reactive Oxygen Species
Yeung-Chul Mun , Jee Young Ahn , Eun Sun Yoo , Kyoung Eun Lee , Eun Mi Nam , Jungwon Huh , Hyun Ae Woo , Sue Goo Rhee , and Chu Myong Seong
Mol. Cells 2020; 43(9): 813-820  https://doi.org/10.14348/molcells.2020.2234 PDF Google Scholar Search
C9orf72-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons
Jeong Hyang Park , Chang Geon Chung , Jinsoo Seo , Byung-Hoon Lee , Young-Sam Lee , Jung Hyun Kweon , and Sung Bae Lee
Mol. Cells 2020; 43(9): 821-830  https://doi.org/10.14348/molcells.2020.0130 PDF Supplementary File(s) Google Scholar Search
Crystal Structure of β-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus
Subin Kim , Jungyoon Yeon , Jongmin Sung , and Mi Sun Jin *
Mol. Cells 2020; 43(9): 831-840  https://doi.org/10.14348/molcells.2020.0168 PDF Google Scholar Search
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Current Issue

30 September 2020
Volume 43,
Number 9,
pp. 763~840
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

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