• Research Article  30 September 2020

    Crystal Structure of β-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus

    The β-class of carbonic anhydrases (β-CAs) are zinc metalloenzymes widely distributed in the fungal kingdom that play essential roles in growth, survival, differentiation, and virulence by catalyzing the reversible interconversion of carbon dioxide (CO2) and bicarbonate (HCO3). Herein, we report the biochemical and crystallographic characterization of the β-CA CafA from the fungal pathogen Aspergillus fumigatus, the main causative agent of invasive a ...

  • Research Article  30 September 2020

    Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase

    Arginine kinase (AK), a bioenergy-related enzyme, is distributed widely in invertebrates. The role of highly conserved histidines in AKs is still unascertained. In this study, the highly conserved histidine 284 (H284) in AK of Daphnia magna (DmAK) was replaced with alanine to elucidate the role of H284. We examined the alteration of catalytic activity and structural changes of H284A in DmAK. The catalytic activity of H284A was reduced dramatically compared to that in wild ty ...

  • Minireview  30 September 2020

    WNT Signaling in Lung Repair and Regeneration

    The lung has a vital function in gas exchange between the blood and the external atmosphere. It also has a critical role in the immune defense against external pathogens and environmental factors. While the lung is classified as a relatively quiescent organ with little homeostatic turnover, it shows robust regenerative capacity in response to injury, mediated by the resident stem/progenitor cells. During regeneration, regionally distinct epithelial cell populations with specific functions are ge ...

  • Minireview  30 September 2020

    Classifying the Linkage between Adipose Tissue Inflammation and Tumor Growth through Cancer-Associated Adipocytes

    Recently, tumor microenvironment (TME) and its stromal constituents have provided profound insights into understanding alterations in tumor behavior. After each identification regarding the unique roles of TME compartments, non-malignant stromal cells are found to provide a sufficient tumorigenic niche for cancer cells. Of these TME constituents, adipocytes represent a dynamic population mediating endocrine effects to facilitate the crosstalk between cancer cells and distant organs, as well as t ...

Mol. Cells 2020; 43(10): 841~898
Histone H4-Specific Deacetylation at Active Coding Regions by Hda1C
Min Kyung Lee and TaeSoo Kim
Mol. Cells 2020; 43(10): 841-847  https://doi.org/10.14348/molcells.2020.0141 PDF Google Scholar Search
Research Articles
The Role of Stress Granules in the Neuronal Differentiation of Stem Cells
Sin-Gu Jeong , Takbum Ohn , Chul Ho Jang , Karthikeyan Vijayakumar , and Gwang-Won Cho ,
Mol. Cells 2020; 43(10): 848-855  https://doi.org/10.14348/molcells.2020.0135 PDF Supplementary File(s) Google Scholar Search
Long Noncoding RNA HOXA11-AS Modulates the Resistance of Nasopharyngeal Carcinoma Cells to Cisplatin via miR-454-3p/c-Met
Feng-Jie Lin , Xian-Dong Lin , Lu-Ying Xu , and Shi-Quan Zhu
Mol. Cells 2020; 43(10): 856-869  https://doi.org/10.14348/molcells.2020.0133 PDF Google Scholar Search
Ataxin-2 Dysregulation Triggers a Compensatory Fragile X Mental Retardation Protein Decrease in Drosophila C4da Neurons
In Jun Cha , Davin Lee , Sung Soon Park , Chang Geon Chung , Seung Yeon Kim , Min Gu Jo , Seung Yeol Kim , Byung-Hoon Lee , Young-Sam Lee , and Sung Bae Lee
Mol. Cells 2020; 43(10): 870-879  https://doi.org/10.14348/molcells.2020.0158 PDF Supplementary File(s) Google Scholar Search
A Database of Caenorhabditis elegans Locomotion and Body Posture Phenotypes for the Peripheral Neuropathy Model
Ki Wha Chung , Ju Seong Kim , and Kyung Suk Lee
Mol. Cells 2020; 43(10): 880-888  https://doi.org/10.14348/molcells.2020.0178 PDF Supplementary File(s) Google Scholar Search
K-Ras–Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated
You-Soub Lee , Ja-Yeol Lee , Soo-Hyun Song , Da-Mi Kim , Jung-Won Lee , Xin-Zi Chi , Yoshiaki Ito , and Suk-Chul Bae
Mol. Cells 2020; 43(10): 889-897  https://doi.org/10.14348/molcells.2020.0182 PDF Supplementary File(s) Google Scholar Search
Retraction Note: Overexpression of Long Non-Coding RNA HOTAIR Promotes Tumor Growth and Metastasis in Human Osteosarcoma
Bo Wang, Yun Su, Qun Yang, Decheng Lv, Weiguo Zhang, Kai Tang, Hong Wang, Rui Zhang, and Yang Liu
Mol. Cells 2020; 43(10): 898-898  https://doi.org/10.14348/molcells.2020.3327 PDF Google Scholar Search
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Current Issue

31 October 2020
Volume 43,
Number 10,
pp. 841~898
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

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