• Article  30 November 2016

    Allele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans

    Regulator of calcineurin 1 (RCAN1) binds to calcineurin through the PxIxIT motif, which is evolutionarily conserved. SP repeat phosphorylation in RCAN1 is required for its complete function. The specific interaction between RCAN1 and calcineurin is critical for calcium/calmodulin-dependent regulation of calcineurin serine/threonine phosphatase activity. In this study, we investigated two available deletion rcan-1 mutants in Caenorhabditis elegans, which proce ...

  • Article  30 November 2016

    Structural and Biochemical Studies Reveal a Putative FtsZ Recognition Site on the Z-ring Stabilizer ZapD

    FtsZ, a tubulin homologue, is an essential protein of the Z-ring assembly in bacterial cell division. It consists of two domains, the N-terminal and C-terminal core domains, and has a conserved C-terminal tail region. Lateral interactions between FtsZ protofilaments and several Z-ring associated proteins (Zaps) are necessary for modulating Z-ring formation. ZapD, one of the positive regulators of Z-ring assembly, directly binds to the C-terminal tail of FtsZ and promotes stable Z-ring formati ...

  • Minireview  30 November 2016

    Epigenetic Changes in Neurodegenerative Diseases

    Afflicted neurons in various neurodegenerative diseases generally display diverse and complex pathological features before catastrophic occurrence of massive neuronal loss at the late stages of the diseases. This complex nature of neuronal pathophysiology inevitably implicates systemwide changes in basic cellular activities such as transcriptional controls and signal cascades, and so on, as a cause. Recently, as one of these systemwide cellular changes associated with neurodegenerative diseas ...

  • Minireview  30 November 2016

    Viral Inhibition of PRR-Mediated Innate Immune Response: Learning from KSHV Evasion Strategies

    The innate immune system has evolved to detect and destroy invading pathogens before they can establish systemic infection. To successfully eradicate pathogens, including viruses, host innate immunity is activated through diverse pattern recognition receptors (PRRs) which detect conserved viral signatures and trigger the production of type I interferon (IFN) and pro-inflammatory cytokines to mediate viral clearance. Viral persistence requires that viruses co-opt cellular pathways and activiti ...


Mol. Cells 2016; 39(11): 777~840
Minireviews
Viral Inhibition of PRR-Mediated Innate Immune Response: Learning from KSHV Evasion Strategies
Hye-Ra Lee, Un Yung Choi, Sung-Woo Hwang, Stephanie Kim, and Jae U. Jung
Mol. Cells 2016; 39(11): 777-782  https://doi.org/10.14348/molcells.2016.0232 PDF PubMed PubReader Google Scholar Search
Epigenetic Changes in Neurodegenerative Diseases
Min Jee Kwon, Sunhong Kim, Myeong Hoon Han, and Sung Bae Lee
Mol. Cells 2016; 39(11): 783-789  https://doi.org/10.14348/molcells.2016.0233 PDF PubMed PubReader Google Scholar Search
Articles
In Vivo Angiogenic Capacity of Stem Cells from Human Exfoliated Deciduous Teeth with Human Umbilical Vein Endothelial Cells
Ji-Hye Kim, Gee-Hye Kim, Jae-Won Kim, Hee Jang Pyeon, Jae Cheoun Lee, Gene Lee, and Hyun Nam
Mol. Cells 2016; 39(11): 790-796  https://doi.org/10.14348/molcells.2016.0131 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Glucose and Insulin Stimulate Lipogenesis in Porcine Adipocytes: Dissimilar and Identical Regulation Pathway for Key Transcription Factors
Zhang Guo Hua, Lu Jian Xiong, Chen Yan, Dai Hong Wei, ZhaXi YingPai, Zhao Yong Qing, Qiao Zi Lin, Feng Ruo Fei, Wang Ya Ling, and Ma Zhong Ren
Mol. Cells 2016; 39(11): 797-806  https://doi.org/10.14348/molcells.2016.0144 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Cell-SELEX Based Identification of an RNA Aptamer for Escherichia coli and Its Use in Various Detection Formats
Pooja Dua, Shuo Ren, Sang Wook Lee, Joon-Ki Kim, Hye-su Shin, OK-Chan Jeong, Soyoun Kim, and Dong-Ki Lee
Mol. Cells 2016; 39(11): 807-813  https://doi.org/10.14348/molcells.2016.0167 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Structural and Biochemical Studies Reveal a Putative FtsZ Recognition Site on the Z-ring Stabilizer ZapD
Hwajung Choi, Kyungjin Min, Bunzo Mikami, Hye-Jin Yoon, and Hyung Ho Lee
Mol. Cells 2016; 39(11): 814-820  https://doi.org/10.14348/molcells.2016.0202 PDF PubMed PubReader Google Scholar Search
STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells
Minkyung Shin, Eun Hee Yi, Byung-Hak Kim, Jae-Cheon Shin, Jung Youl Park, Chung-Hyun Cho, Jong-Wan Park, Kang-Yell Choi, and Sang-Kyu Ye
Mol. Cells 2016; 39(11): 821-826  https://doi.org/10.14348/molcells.2016.0212 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Allele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans
Weixun Li, Tae-Woo Choi, Joohong Ahnn, and Sun-Kyung Lee
Mol. Cells 2016; 39(11): 827-833  https://doi.org/10.14348/molcells.2016.0222 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
LIN-23, an E3 Ubiquitin Ligase Component, Is Required for the Repression of CDC-25.2 Activity during Intestinal Development in Caenorhabditis elegans
Miseol Son, Ichiro Kawasaki, Bong-Kyeong Oh, and Yhong-Hee Shim
Mol. Cells 2016; 39(11): 834-840  https://doi.org/10.14348/molcells.2016.0238 PDF PubMed PubReader Google Scholar Search
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Current Issue

30 November 2016
Volume 39,
Number 11,
pp. 777~840
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

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