• Research Article  31 July 2020

    High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in Arabidopsis

    Leaf senescence is a developmental process by which a plant actively remobilizes nutrients from aged and photosynthetically inefficient leaves to young growing ones by disassembling organelles and degrading macromolecules. Senescence is accelerated by age and environmental stresses such as prolonged darkness. Phytochrome B (phyB) inhibits leaf senescence by inhibiting phytochrome-interacting factor 4 (PIF4) and PIF5 in prolonged darkness. However, it remains unknown whether phyB mediates the tem ...

  • Research Article  31 July 2020

    PARP1 Impedes SIRT1-Mediated Autophagy during Degeneration of the Retinal Pigment Epithelium under Oxidative Stress

    The molecular mechanism underlying autophagy impairment in the retinal pigment epithelium (RPE) in dry age-related macular degeneration (AMD) is not yet clear. Based on the causative role of poly(ADP-ribose) polymerase 1 (PARP1) in RPE necrosis, this study examined whether PARP1 is involved in the autophagy impairment observed during dry AMD pathogenesis. We found that autophagy was downregulated following H2O2-induced PARP1 activation in ARPE-19 cells and olaparib, PARP1 i ...

  • Minireview  31 July 2020

    Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology

    Complex cell-to-cell communication underlies the basic processes essential for homeostasis in the given tissue architecture. Obtaining quantitative gene-expression of cells in their native context has significantly advanced through single-cell RNA sequencing technologies along with mechanical and enzymatic tissue manipulation. This approach, however, is largely reliant on the physical dissociation of individual cells from the tissue, thus, resulting in a library with unaccounted positional infor ...

  • Minireview  31 July 2020

    Ultradian Rhythms in the Hypothalamic Arcuate Nucleus Kisspeptin Neurons and Developmental Processes

    Numerous physiological processes in nature have multiple oscillations within 24 h, that is, ultradian rhythms. Compared to the circadian rhythm, which has a period of approximately one day, these short oscillations range from seconds to hours, and the mechanisms underlying ultradian rhythms remain largely unknown. This review aims to explore and emphasize the implications of ultradian rhythms and their underlying regulations. Reproduction and developmental processes show ultradian rhythms, and t ...


Mol. Cells 2020; 43(7): 591~670
Minireviews
Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology
Joji Marie Teves and Kyoung Jae Won
Mol. Cells 2020; 43(7): 591-599  https://doi.org/10.14348/molcells.2020.0020 PDF PubMed PubMed Central PubReader Google Scholar Search
Ultradian Rhythms in the Hypothalamic Arcuate Nucleus Kisspeptin Neurons and Developmental Processes
Doyeon Kim , Han Kyoung Choe , and Kyungjin Kim
Mol. Cells 2020; 43(7): 600-606  https://doi.org/10.14348/molcells.2020.0066 PDF PubMed PubMed Central PubReader Google Scholar Search
Research Articles
Enhancer Function of MicroRNA-3681 Derived from Long Terminal Repeats Represses the Activity of Variable Number Tandem Repeats in the 3’ UTR of SHISA7
Hee-Eun Lee , Sang-Je Park , Jae-Won Huh , Hiroo Imai , and Heui-Soo Kim
Mol. Cells 2020; 43(7): 607-618  https://doi.org/10.14348/molcells.2020.0058 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
Characterization of TNNC1 as a Novel Tumor Suppressor of Lung Adenocarcinoma
Suyeon Kim , Jaewon Kim , Yeonjoo Jung , Yukyung Jun , Yeonhwa Jung , Hee-Young Lee , Juhee Keum , Byung Jo Park , Jinseon Lee , Jhingook Kim , Sanghyuk Lee , and Jaesang Kim
Mol. Cells 2020; 43(7): 619-631  https://doi.org/10.14348/molcells.2020.0075 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
PARP1 Impedes SIRT1-Mediated Autophagy during Degeneration of the Retinal Pigment Epithelium under Oxidative Stress
Ki-Hong Jang , Yeseong Hwang , and Eunhee Kim
Mol. Cells 2020; 43(7): 632-644  https://doi.org/10.14348/molcells.2020.0078 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in Arabidopsis
Chanhee Kim , Sun Ji Kim, Jinkil Jeong , Eunae Park , Eunkyoo Oh , Youn-Il Park , Pyung Ok Lim , and Giltsu Choi
Mol. Cells 2020; 43(7): 645-661  https://doi.org/10.14348/molcells.2020.0117 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
PRP4 Kinase Domain Loss Nullifies Drug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells
Muhammad Bilal Ahmed , Salman Ul Islam , Jong Kyung Sonn , and Young Sup Lee
Mol. Cells 2020; 43(7): 662-670  https://doi.org/10.14348/molcells.2020.2263 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
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Current Issue

31 July 2020
Volume 43,
Number 7,
pp. 591~670
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*


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