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Fig. 5.

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Fig. 5. The zinc ion is coordinated by H107, H109, H126, and an exchangeable fourth ligand; a bicarbonate (A), a water molecule (B), or acetazolamide (C). The zinc ion is shown as a gray sphere. The Fo-Fc map superimposed on the refined bicarbonate, water, and acetazolamide is contoured at 4σ, 3σ, and 3.5σ levels, respectively. (D) Surface representation of pmCA showing the spatial distribution of hydrophilicity and hydrophobicity in the cavity. Green, hydrophilic; white, hydrophobic.
Mol. Cells 2019;42:460~469 https://doi.org/10.14348/molcells.2019.0029
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