Molecules and Cells

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Fig. 4.

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Fig. 4. Three or 6 week-old AF mice were switched to the SPF condition for 2 weeks. IELs were harvested and analyzed for CD8αβ+ T cells. Representative dot plots show the frequencies of the CD8αβ+ IELs in the indicated mice after gating CD45+TCRγδ-TCRαβ+ cells (left). The graph shows the absolute numbers of TCRαβ+CD8αβ+ IELs (right). Numbers in dot plots indicate the frequency of cells in adjacent gates. Each dot represents an individual mouse and horizontal bars indicate mean values. *P < 0.05, **P < 0.01 (unpaired t-test). Error bars indicate SD. IEL, intraepithelial lymphocyte
Mol. Cells 2019;42:313~320
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