Molecules and Cells

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Fig. 1.

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Fig. 1. (A) Three-week old SPF mice were weaned onto either standard diet (STD) or antigen-free diet (AFD) and analyzed for the development of CD8αβ+ IELs. Shown are representative dot plots of gated TCRαβ+ cells (left). Graph shows their absolute numbers (right). (B) Representative dot plots show IELs with indicated phenotype in 2, 4 or 6 week-old SPF or GF mice (left). Graph shows absolute numbers of CD8αβ+ IELs (right upper) and TCRγδ IELs (right lower) at indicated time points. Numbers indicate the frequencies of cells in adjacent gates. Each dot represents an individual mouse and horizontal bars indicate mean values. *P < 0.05 (unpaired t-test). Error bars indicate SD. IEL, intraepithelial lymphocytes.
Mol. Cells 2019;42:313~320
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