Molecules and Cells

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Fig. 5.

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Fig. 5. (A) 2 days after infection, the trypsinized cells were plated in 96-well plate, and cell proliferation was examined for upto 15 days. Note that U2AF1 S34 mutant-expressing cells grew in a robust manner after initially stunted cell division. (B) U2AF1 S34 mutant-expressing cells grew via clonal expansion. Virus-transduced cells were cultured for 15 days in 35mm plates. Note the clonal expansion of S34F mutant -expressing cells after presumptive apoptosis of most of the cells.
Mol. Cells 2018;41:733~741
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