Molecules and Cells

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Fig. 1.

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Fig. 1. Mechanisms of H2O2 sensing. In (A) the three mechanisms investigated in these proposal are shown: (1) direct oxidation of the signaling protein (SP) by H2O2; oxidation of SP is mediated by (2) a peroxiredoxin (Prx) or by (3) a thioredoxin (Trx). In (B) the overoxidation of a Prx is shown, which leads to H2O2 accumulation.
Mol. Cells 2016;39:65~71
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